Powering Lifelong Health
Developing first-in-class NAD+ restoration therapies to recharge cellular energy and combat age-related diseases.
NAD+ depletion drives
the hallmarks of aging
Nicotaminide Adenine Dinucleotide (NAD+) is an essential molecule that powers every living cell in our bodies to perform its vital function(s).
The problem is our bodies don’t have an unlimited supply of NAD+. As we grow older our cells become deprived of the energy they need to carry out their normal physiological functions, leading to cellular exhaustion and the onset of age-related diseases.
The problem is our bodies don’t have an unlimited supply of NAD+. As we grow older our cells become deprived of the energy they need to carry out their normal physiological functions, leading to cellular exhaustion and the onset of age-related diseases.
Our Solution
NAD+ restoration by PNP Inhibition
metaShape Pharma is developing a proprietary, best-in-class inhibitor of purine nucleoside phosophorylase (PNP) to reliably restore the body’s ability to synthesise NAD+, recharge cellular energy to its full power and treat age-related diseases.
What makes MS 001 remarkable
MS 001 is a potent, selective PNP inhibitor that combines the safety of a drug established from Phase I and II studies with the ground-breaking potential of a new, patented chemical entity with a novel method of use that outperforms traditional NAD+ precursors.
Where We’re Headed
Our development strategy follows a stepwise approach, starting by addressing well-defined, age-related disorders with a high unmet need, to addressing more complex diseases with tremendous implications for longevity.
Our target indications:
Reduction of LDL cholesterol in patients with statin intolerance.
Prevention of cognitive decline.
Treatment of neurodegenerative diseases. About
Founded in 2023, metaShape Pharma is a privately-held, Swiss longevity therapeutics company developing first-in-class NAD+ restoration therapies for ageing disorders.
Our accomplished founding-leadership team brings decades of expertise in internal medicine, drug development and PNP inhibition, as well as a deeply personal drive to turn the tables on age-related disease.
Our Latest News
3 Sep, 2023
By Kevin Martin 
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3 Sep, 2023
By Kevin Martin 5 Comments
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3 Sep, 2023
By Kevin Martin 1 Comments Lorem ipsum dolor sit amet, adipiscing elit.
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