MetaShape

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Powering Lifelong Health

Developing first-in-class NAD+ restoration therapies to recharge cellular energy and combat age-related diseases.

NAD+ metaShape Pharma

NAD+ depletion drives
the hallmarks of aging 

Nicotaminide Adenine Dinucleotide (NAD+) is an essential molecule that powers every living cell in our bodies to perform its vital function(s).

The problem is our bodies don’t have an unlimited supply of NAD+. As we grow older our cells become deprived of the energy they need to carry out their normal physiological functions, leading to cellular exhaustion and the onset of age-related diseases.
NAD+ metaShape Pharma
NAD+ restoration by PNP Inhibition

Our Solution

NAD+ restoration by PNP Inhibition

metaShape Pharma is developing a proprietary, best-in-class inhibitor of purine nucleoside phosophorylase (PNP) to reliably restore the body’s ability to synthesise NAD+, recharge cellular energy to its full power and treat age-related diseases.

metshapepharma MS 001

What makes MS 001 remarkable

MS 001 is a potent, selective PNP inhibitor that combines the safety of a drug established from Phase I and II studies with the ground-breaking potential of a new, patented chemical entity with a novel method of use that outperforms traditional NAD+ precursors.
metshapepharma MS 001
NAD+ Metashapepharma

Where We’re Headed

Our development strategy follows a stepwise approach, starting by addressing well-defined, age-related disorders with a high unmet need, to addressing more complex diseases with tremendous implications for longevity.

Our target indications:

  Reduction of LDL cholesterol in patients with statin intolerance.
  Prevention of cognitive decline.
  Treatment of neurodegenerative diseases.

About

metashapepharma logo
Founded in 2023, metaShape Pharma is a privately-held, Swiss longevity therapeutics company developing first-in-class NAD+ restoration therapies for ageing disorders.
Our accomplished founding-leadership team brings decades of expertise in internal medicine, drug development and PNP inhibition, as well as a deeply personal drive to turn the tables on age-related disease.

Our Latest News

3 Sep, 2023

  By Kevin Martin    2 Comments

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3 Sep, 2023

  By Kevin Martin   5  Comments

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3 Sep, 2023

  By Kevin Martin    1 Comments

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CONTACT

Power lifelong health with us

Invest in groundbreaking science that redefines aging and disease management

Email

info@metashapepharma.com

Address

Rütiring 6, Riehen, 4125, Basel, Switzerland